JPINFV Posted November 7, 2007 Share Posted November 7, 2007 Just wondering, in case I missed somehting, is there any reason why it couldn't be Reye's Syndrome? Link to comment Share on other sites More sharing options...
Just Plain Ruff Posted November 7, 2007 Share Posted November 7, 2007 a good suggestion. We could be dealing with both. Good info here http://www.reyessyndrome.org/what.htm Both conditions Reye's and Aspirin overdose look similar. Link to comment Share on other sites More sharing options...
JPINFV Posted November 7, 2007 Share Posted November 7, 2007 Reye's is a multi-factal mitochondria associated encephalomyopathy involving children, viral infections, and aspirin. Symptoms can include vomiting, coma, hepatomegaly, and hypoglycemia. Mitochondria related etiology mostly involves disruption in the mitochonria protein import complexes. Link to comment Share on other sites More sharing options...
ERDoc Posted November 7, 2007 Share Posted November 7, 2007 This pt has not taken any aspirin, only tylenol and motrin. Why would he have Reye's? Link to comment Share on other sites More sharing options...
JPINFV Posted November 7, 2007 Share Posted November 7, 2007 Symptoms fit so far (vomiting, declining LOC, I'm sure I'm missing some because the course was focused on the mechanism more) with a commnity infection consistant with a viral infection. The parents at this time don't seem to be the best historians since they seem to be adding things every 5 minutes or so. Also, (browsing though a few different websites), it seems that it's not just ASA, but salicylic acid in general [http://www.reyessyndrome.org/aspirin.htm] that is related to Reye's. This includes pepto bismol. Besides, I think it would be cool if something I learned about a few weeks ago was a solution to the scenario. Edit: grammar, clarifications Link to comment Share on other sites More sharing options...
Just Plain Ruff Posted November 7, 2007 Share Posted November 7, 2007 Doc, doesn't pepto have a derivative of Salycilates in it? Link to comment Share on other sites More sharing options...
Chief1C Posted November 7, 2007 Share Posted November 7, 2007 the subsalicylate in pepto is non-aspirin Link to comment Share on other sites More sharing options...
Just Plain Ruff Posted November 7, 2007 Share Posted November 7, 2007 True cmk but salicylates have been associated with Reyes for a long time if I remember reading that somewhere. So even though the salicylates in pepto are non-aspirin they still have the feasible possibility to cause Reyes. From EMED article I posted above Background: Salicylates are ubiquitous agents found in hundreds of over-the-counter (OTC) medications and in numerous prescription drugs. Salicylic acid and its derivatives are active ingredients in a wide variety of readily available topical preparations used for the treatment of pain, warts, and acne. Pepto-Bismol, a common antidiarrheal agent, contains 131 mg of salicylate per tablespoon. Salicylate ingestion continues to be a common cause of poisoning in children and adolescents. The prevalence of aspirin-containing analgesic products makes these agents, found in virtually every household, common sources of both accidental and suicidal ingestion So an overdose of aspirin or salycilates(I can't seem to get that spelling right) with a side order of possible reyes syndrome is entirely possible for this kid. Link to comment Share on other sites More sharing options...
hammerpcp Posted November 7, 2007 Share Posted November 7, 2007 yay Link to comment Share on other sites More sharing options...
Chief1C Posted November 7, 2007 Share Posted November 7, 2007 Suicide by constipation? Link to comment Share on other sites More sharing options...
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