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ABO Blood Type Is a Risk Factor for Coronary Heart Disease


DFIB

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The results of this study are a little starling and interesting as well.

August 14, 2012 (Boston, Massachusetts) — Data from two prospective cohort studies have identified the ABO blood group as a risk factor for the development of coronary heart disease [1]. Individuals with blood groups A, B, or AB were 5% to 23% more likely to develop coronary heart disease compared with subjects with O blood type, and the associations were not altered by multivariate adjustment of other risk or dietary factors.

The analysis, led by Dr Meian He (Harvard School of Public Health, Boston, MA), included 62 073 women from the Nurses' Health Study(NHS) and 27 428 men from the Health Professionals Follow-up Study (HPFS) and is published in the September 2012 issue ofArteriosclerosis, Thrombosis, and Vascular Biology.

In the NHS and HPFS, the incident rates of coronary heart disease per 100 000 person-years were 125, 128, 142, and 161 for women with type O, A, B, and AB, respectively, and 373, 382, 387, and 524 for men with type O, A, B, and AB, respectively. Compared with individuals with O blood type, individuals with blood group A, B, or AB had a respective 5%, 11%, and 23% increased risk of developing coronary heart disease in an age-adjusted model. These associations were not significantly altered in the multivariable-adjusted risk model. Michael O’Riordan, Heartwire © 2012 Medscape, LLC

You can read the complete article Here, but you have to log in first.

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