Jump to content

Low dose Dopamine


donedeal

Recommended Posts

Are any of you using Dopamine in your Non-traumatic resuscitated cardiac arrest patients, who DO have a decent BP, specifically for its perfusion effects? At 1-2mcg/kg/min Dopamine stimulates D-receptors dilating not only renal but cerebral and mesenteric vasculature. Combined with fluids to help dilute toxin buildup from a once non-perfusing patient, wouldn't dilation to these organs possibly reduce morbidity in the post arrest patient?

Link to comment
Share on other sites

Are any of you using Dopamine in your Non-traumatic resuscitated cardiac arrest patients, who DO have a decent BP, specifically for its perfusion effects? At 1-2mcg/kg/min Dopamine stimulates D-receptors dilating not only renal but cerebral and mesenteric vasculature. Combined with fluids to help dilute toxin buildup from a once non-perfusing patient, wouldn't dilation to these organs possibly reduce morbidity in the post arrest patient?

Not in post arrest, however in sepsis I have seen it given to "kik start" the kidneys in a non-hypotensive patient with an incresing lactate and decreasing Sp02.

Link to comment
Share on other sites

No, the current thinking on that is that it's ineffective and doesn't have any real benefit. (I can't recall since I haven't looked in awhile but I don't think it was detrimental, just didn't have any benefits). If they are truly normotensive, then generally (or maybe sometimes) they should be perfusing well enough until you can get more information. Different conditions will have different problems though; like sepsis where even "normotensive" patient's may be on pressors or getting transfused.

Link to comment
Share on other sites

Are any of you using Dopamine in your Non-traumatic resuscitated cardiac arrest patients, who DO have a decent BP, specifically for its perfusion effects? At 1-2mcg/kg/min Dopamine stimulates D-receptors dilating not only renal but cerebral and mesenteric vasculature. Combined with fluids to help dilute toxin buildup from a once non-perfusing patient, wouldn't dilation to these organs possibly reduce morbidity in the post arrest patient?

I think the idea of low-dose dopamine has acting via dopaminergic effects has been debunked about 10 years ago. As I recall, it was determined that at low doses we were seeing greater urine output due to an increase in MAP and renal perfusion pressure that was due to beta-adrenoceptor activation, versus any specific renovascular effects through the DA receptors.

Link to comment
Share on other sites

  • 2 weeks later...

I have seen low dose Dopamine used in the ICU by both Cardiologist & Intensivist. They usually would start at 2.5 mcg/kg/min. It was helpful especially for people who had bradycardia, lower blood pressure & also decreased urinary output.

Link to comment
Share on other sites

This thread is quite old. Please consider starting a new thread rather than reviving this one.

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...