Abandoning Fentanyl? in Patient Care Posted April 19, 2019 Yes. Fentanyl is addictive with potential for misuse. Morphine is also addictive with potential for abuse. As are the benzos we carry for seizures/sedation. Ketamine? Well, that's so blatantly addictive/misused that it has it's own street name. When used appropriately it is exceptionally effective. With what do you suggest it be replaced?